Selank (5 mg vial)
Once daily subcutaneous, 4 weeks on / 4 weeks off protocol for cognitive and neurological research.
Selank is a tuftsin analog developed as a non-sedating anxiolytic in the Russian peptide tradition, studied for taking the edge off without impairment. The protocol below runs once daily in four-week on and off cycles.
Quick answer: at the standard 5 mg + 0.5 mL reconstitution, a 500 mcg dose of Selank draws 5 units (0.05 mL) on a U-100 insulin syringe, once daily subcutaneous, 4 weeks on / 4 weeks off.
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Protocol overview
Dosing & reconstitution
Frequency: Once daily subcutaneous, 4 weeks on / 4 weeks off
Typical duration: 4-week cycles
Reconstitution: 5 mg vial + 0.5 mL bacteriostatic water = 10 mg/mL. Units below are for a U-100 insulin syringe at this concentration.
| Phase | Dose | Units per injection |
|---|---|---|
| Weeks 1-2 | 300 mcg | 3 units (0.03 mL) |
| Weeks 3-4 | 500 mcg | 5 units (0.05 mL) |
Units = (dose ÷ concentration) × 100 on a U-100 syringe. Change the vial size or water volume and the calculator redoes all of this for you.
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Selank dosing schedule
Like Semax, Selank is registered in Russia as an intranasal solution and studied there in generalised anxiety indications. The same two caveats apply: the literature is largely Russian-language, and the registered product is nasal drops rather than the injectable research vial.
| Phase | Amount | Frequency | Notes |
|---|---|---|---|
| Registered intranasal use | 0.15% solution | Drops per nostril, daily | The registered presentation, expressed as drops of a stated concentration. |
Study length: Courses of roughly 14 days appear in the published clinical work.
Reconstitution and measurement
This part is arithmetic and does not depend on the evidence level. Concentration is vial size divided by the bacteriostatic water you add. Draw volume is your target amount divided by that concentration. Units are draw volume times 100, because a U-100 syringe reads 100 units per millilitre. Common vials for Selank: 10 mg.
- Wipe the stoppers of both vials with an alcohol swab and let them dry.
- Draw the bacteriostatic water with a sterile syringe and inject it slowly down the inside wall of the peptide vial — never straight onto the powder.
- Swirl gently until the solution is clear. Do not shake; foaming and agitation damage peptides.
- Label the vial with the date and concentration, and refrigerate at 2–8 °C protected from light.
Worked example at the calculator defaults: 10 mg + 2 mL of bacteriostatic water = 5 mg/mL, so on a U-100 insulin syringe 1 unit = 50 mcg of Selank. Change either input and the calculator redoes this for you.
Storage and stability
Important notes
Practical considerations for consistency and safety.
- Use a new sterile insulin syringe for each injection and dispose in a proper sharps container.
- Inject slowly and steadily; wait a few seconds before withdrawing the needle to ensure complete delivery.
- Administer at the same time each day for consistent levels. Setting a daily reminder helps maintain the schedule.
- The 5 mg vial size is standard for this compound. Reconstitute with 0.5 mL bacteriostatic water for a convenient concentration.
How Selank works
A synthetic analog of the immunopeptide tuftsin, again with a Pro-Gly-Pro tail for stability. It is studied as an anxiolytic without the sedation or dependence associated with benzodiazepines, with effects reported on GABAergic and monoamine signalling.
Benefits & side effects
Potential benefits
- Anxiolytic peptide with cognitive benefits
- Supports GABA and serotonin modulation
- Reduces anxiety without sedation
- Cycling recommended (4 on / 4 off)
Possible side effects
- Injection site reactions
- Mild sedation in some users
- Generally well tolerated
- Fatigue reported occasionally
This list reflects published literature and community reports. Individual responses vary. Not medical advice.
Bloodwork worth tracking
The community-standard practice is a baseline panel before starting, a recheck 8 to 12 weeks in, and another after time off. For Selank, the markers most worth watching:
CMPCBC
Typical time off: 4 wks off between cycles
Lab panels are how a research protocol stays honest: numbers move before symptoms do. Interpretation belongs with a clinician. Not medical advice.
Lifestyle factors
None of the literature above was run on a background of poor sleep and no protein. These variables move outcomes more reliably than any compound on this site.
- Protein in the 1.6 to 2.2 g/kg range preserves lean mass through any body-composition phase.
- Resistance training 2 to 4 days per week plus 150+ minutes of weekly aerobic work reinforces whatever the protocol is doing.
- Sleep is the recovery window: 7 to 9 hours at consistent times.
- Hydration matters more than usual on compounds with GI or flushing effects: 2 to 3 liters daily.
- Track the variables that matter: weigh-ins, measurements, photos, and labs at sensible intervals.
References
Quick answers
How many syringe units is a 500 mcg dose of Selank?
At the standard reconstitution of 5 mg with 0.5 mL bacteriostatic water (10 mg/mL), a 500 mcg dose draws 5 units (0.05 mL) on a U-100 insulin syringe.
How do you reconstitute Selank?
Add 0.5 mL of bacteriostatic water to the 5 mg vial for 10 mg/mL. Inject the water slowly down the inside wall of the vial, swirl gently without shaking, and refrigerate at 2 to 8 °C after mixing.
How long does a 5 mg vial of Selank last?
About 10 maintenance doses of 500 mcg, roughly 1.4 weeks at once daily subcutaneous, 4 weeks on / 4 weeks off.
Does Selank have human trial data?
Yes. The dosing on this page is anchored to published human research (Selank clinical literature (Russian registration, anxiety indications)).
How does Selank work?
A synthetic analog of the immunopeptide tuftsin, again with a Pro-Gly-Pro tail for stability. It is studied as an anxiolytic without the sedation or dependence associated with benzodiazepines, with effects reported on GABAergic and monoamine signalling.
Sourcing Selank
Whatever you are working with, the documentation matters more than the price. Ask for a batch certificate of analysis whose lot number matches the vial you actually receive — a COA for a different batch tells you nothing about yours.
Selank at Summit Research Supply → Grade a COA first
Summit is the supplier we feature and an affiliate link. Our COA checklist applies the same way to any vendor.
