Tesamorelin + Ipamorelin (15 mg vial)
Once daily subcutaneous at bedtime protocol for growth hormone axis research.
This stack pairs the clinically proven GHRH analog with the cleanest GHRP, aimed at body composition and visceral fat rather than general recovery. The protocol below is one bedtime subcutaneous injection covering both.
Quick answer: at the standard 15 mg + 1.5 mL reconstitution, a 1 mg total dose of Tesamorelin + Ipamorelin draws 10 units (0.1 mL) on a U-100 insulin syringe, once daily subcutaneous at bedtime.
Get Tesamorelin + Ipamorelin → code PEPDOSE
Protocol overview
Dosing & reconstitution
Frequency: Once daily subcutaneous at bedtime
Typical duration: 8-12 weeks
Reconstitution: 15 mg vial + 1.5 mL bacteriostatic water = 10 mg/mL. Units below are for a U-100 insulin syringe at this concentration.
| Phase | Dose | Units per injection |
|---|---|---|
| Weeks 1-2 | 500 mcg total | 5 units (0.05 mL) |
| Weeks 3-4 | 750 mcg total | 7.5 units (0.075 mL) |
| Weeks 5-8 | 1 mg total | 10 units (0.1 mL) |
Units = (dose ÷ concentration) × 100 on a U-100 syringe. Change the vial size or water volume and the calculator redoes all of this for you.
Track this protocol → Free account · log doses, rotate sites, never lose your history
Tesamorelin + Ipamorelin dosing — what the literature actually supports
We publish a schedule when there is a citable human source and we say so when there is not. Filling this space with a number nobody measured would make the page look more complete and be worth less than nothing to you.
Reconstitution and measurement
This part is arithmetic and does not depend on the evidence level. Concentration is vial size divided by the bacteriostatic water you add. Draw volume is your target amount divided by that concentration. Units are draw volume times 100, because a U-100 syringe reads 100 units per millilitre. Common vials for Tesamorelin + Ipamorelin: 15 mg total.
- Wipe the stoppers of both vials with an alcohol swab and let them dry.
- Draw the bacteriostatic water with a sterile syringe and inject it slowly down the inside wall of the peptide vial — never straight onto the powder.
- Swirl gently until the solution is clear. Do not shake; foaming and agitation damage peptides.
- Label the vial with the date and concentration, and refrigerate at 2–8 °C protected from light.
Open the Tesamorelin + Ipamorelin calculator → Unit converter
Storage and stability
Supplies math
Whatever amounts your research uses, the planning arithmetic is the same. The calculator runs all of this per compound.
Supplies by protocol length
Based on the maintenance dose above (1 mg total, once daily subcutaneous at bedtime) and a 15 mg vial reconstituted with 1.5 mL.
| Duration | Injections | Vials | Syringes | Bac water | Swabs |
|---|---|---|---|---|---|
| 8 weeks | 56 | 4 x 15 mg | 62 | 1 x 10 mL | 112 |
| 12 weeks | 84 | 6 x 15 mg | 93 | 1 x 10 mL | 168 |
| 16 weeks | 112 | 8 x 15 mg | 124 | 2 x 10 mL | 224 |
Syringe count includes ~10% spares. Swabs = 2 per injection (stopper + site). Vial count assumes the full maintenance dose for the entire duration.
Important notes
Practical considerations for consistency and safety.
- Use a new sterile insulin syringe for each injection and dispose in a proper sharps container.
- Rotate injection sites (abdomen, thighs, upper arms) systematically to reduce local irritation and avoid lipohypertrophy.
- Inject slowly and steadily; wait a few seconds before withdrawing the needle to ensure complete delivery.
- Administer at the same time each day for consistent levels. Setting a daily reminder helps maintain the schedule.
- This compound lacks controlled human safety data. Start with the lowest reported amount and increase gradually while monitoring for any adverse reactions.
- The 15 mg vial size is standard for this compound. Reconstitute with 1.5 mL bacteriostatic water for a convenient concentration.
How Tesamorelin + Ipamorelin works
Combines an approved GHRH analog with a ghrelin-receptor agonist in one vial, on the same two-receptor rationale as the CJC/ipamorelin pairing but using the stabilised GHRH analog.
Benefits & side effects
Potential benefits
- Combines GHRH + GHRP for synergistic GH release
- Bedtime dosing aligns with natural GH pulse
- Both compounds have clinical data
- Enhanced GH response vs either alone
Possible side effects
- Combined side effects of both compounds
- Injection site reactions
- Joint pain possible
- Monitor IGF-1 levels
This list reflects published literature and community reports. Individual responses vary. Not medical advice.
Bloodwork worth tracking
The community-standard practice is a baseline panel before starting, a recheck 8 to 12 weeks in, and another after time off. For Tesamorelin + Ipamorelin, the markers most worth watching:
IGF-1fasting glucoselipid panel
Typical time off: 4-8 wks
Lab panels are how a research protocol stays honest: numbers move before symptoms do. Interpretation belongs with a clinician. Not medical advice.
Lifestyle factors
None of the literature above was run on a background of poor sleep and no protein. These variables move outcomes more reliably than any compound on this site.
- Protein in the 1.6 to 2.2 g/kg range preserves lean mass through any body-composition phase.
- Resistance training 2 to 4 days per week plus 150+ minutes of weekly aerobic work reinforces whatever the protocol is doing.
- Sleep is the recovery window: 7 to 9 hours at consistent times.
- Hydration matters more than usual on compounds with GI or flushing effects: 2 to 3 liters daily.
- Track the variables that matter: weigh-ins, measurements, photos, and labs at sensible intervals.
Subcutaneous technique and practical notes
General best practice from clinical injection guidance — the same fundamentals nurses are taught, none of it specific to any compound.
Quick answers
How many syringe units is a 1 mg total dose of Tesamorelin + Ipamorelin?
At the standard reconstitution of 15 mg with 1.5 mL bacteriostatic water (10 mg/mL), a 1 mg total dose draws 10 units (0.1 mL) on a U-100 insulin syringe.
How do you reconstitute Tesamorelin + Ipamorelin?
Add 1.5 mL of bacteriostatic water to the 15 mg vial for 10 mg/mL. Inject the water slowly down the inside wall of the vial, swirl gently without shaking, and refrigerate at 2 to 8 °C after mixing.
How long does a 15 mg vial of Tesamorelin + Ipamorelin last?
About 15 maintenance doses of 1 mg total, roughly 2.1 weeks at once daily subcutaneous at bedtime.
Does Tesamorelin + Ipamorelin have human trial data?
No. The evidence base is animal and cell studies; the practical dosing shown is community convention, and the page labels it that way.
How does Tesamorelin + Ipamorelin work?
Combines an approved GHRH analog with a ghrelin-receptor agonist in one vial, on the same two-receptor rationale as the CJC/ipamorelin pairing but using the stabilised GHRH analog.
Sourcing Tesamorelin + Ipamorelin
Whatever you are working with, the documentation matters more than the price. Ask for a batch certificate of analysis whose lot number matches the vial you actually receive — a COA for a different batch tells you nothing about yours.
Tesamorelin + Ipamorelin Blend at Summit Research Supply → Grade a COA first
Summit is the supplier we feature and an affiliate link. Our COA checklist applies the same way to any vendor.
