GHRP-6 (5 mg vial)
Three times daily subcutaneous protocol for growth hormone axis research.
GHRP-6 is an early ghrelin mimetic known for pronounced GH release and the strongest appetite stimulation in the class, which some research uses deliberately. The protocol below runs three daily subcutaneous doses.
Quick answer: at the standard 5 mg + 0.5 mL reconstitution, a 300 mcg x3 daily dose of GHRP-6 draws 3 units (0.03 mL) x3 on a U-100 insulin syringe, three times daily subcutaneous.
Protocol overview
Dosing & reconstitution
Frequency: Three times daily subcutaneous
Typical duration: 8-12 weeks
Reconstitution: 5 mg vial + 0.5 mL bacteriostatic water = 10 mg/mL. Units below are for a U-100 insulin syringe at this concentration.
| Phase | Dose | Units per injection |
|---|---|---|
| Weeks 1-2 | 100 mcg x3 daily | 1 unit (0.01 mL) x3 |
| Weeks 3-4 | 200 mcg x3 daily | 2 units (0.02 mL) x3 |
| Weeks 5-12 | 300 mcg x3 daily | 3 units (0.03 mL) x3 |
Units = (dose ÷ concentration) × 100 on a U-100 syringe. Change the vial size or water volume and the calculator redoes all of this for you.
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GHRP-6 dosing schedule
GHRP-6 has been used in human GH-secretion research since the 1980s, typically as a single provocative intravenous dose to study pituitary response. There is no approved therapeutic indication and no established treatment course.
| Phase | Amount | Frequency | Notes |
|---|---|---|---|
| Research provocative dose | 1 mcg/kg | Single intravenous dose | The amount commonly used in GH-secretion research. |
Study length: Single administration in the provocative-test setting.
Reconstitution and measurement
This part is arithmetic and does not depend on the evidence level. Concentration is vial size divided by the bacteriostatic water you add. Draw volume is your target amount divided by that concentration. Units are draw volume times 100, because a U-100 syringe reads 100 units per millilitre. Common vials for GHRP-6: Not stocked by our featured supplier.
- Wipe the stoppers of both vials with an alcohol swab and let them dry.
- Draw the bacteriostatic water with a sterile syringe and inject it slowly down the inside wall of the peptide vial — never straight onto the powder.
- Swirl gently until the solution is clear. Do not shake; foaming and agitation damage peptides.
- Label the vial with the date and concentration, and refrigerate at 2–8 °C protected from light.
Storage and stability
Supplies math
Whatever amounts your research uses, the planning arithmetic is the same. The calculator runs all of this per compound.
Supplies by protocol length
Based on the maintenance dose above (300 mcg x3 daily, three times daily subcutaneous) and a 5 mg vial reconstituted with 0.5 mL.
| Duration | Injections | Vials | Syringes | Bac water | Swabs |
|---|---|---|---|---|---|
| 8 weeks | 168 | 11 x 5 mg | 185 | 1 x 10 mL | 336 |
| 12 weeks | 252 | 16 x 5 mg | 278 | 1 x 10 mL | 504 |
| 16 weeks | 336 | 21 x 5 mg | 370 | 2 x 10 mL | 672 |
Syringe count includes ~10% spares. Swabs = 2 per injection (stopper + site). Vial count assumes the full maintenance dose for the entire duration.
Important notes
Practical considerations for consistency and safety.
- Use a new sterile insulin syringe for each injection and dispose in a proper sharps container.
- Inject slowly and steadily; wait a few seconds before withdrawing the needle to ensure complete delivery.
- Administer at the same time each day for consistent levels. Setting a daily reminder helps maintain the schedule.
- The 5 mg vial size is standard for this compound. Reconstitute with 0.5 mL bacteriostatic water for a convenient concentration.
How GHRP-6 works
The earliest of the growth-hormone-releasing hexapeptides and the compound that led to the discovery of the ghrelin receptor. It is a strong GH releaser and a strong appetite stimulant — the hunger is a pronounced, well-documented effect rather than an incidental one.
Benefits & side effects
Potential benefits
- Strong GH release through ghrelin receptor
- Significant appetite stimulation
- Supports recovery and body composition
- Budget-friendly GH secretagogue
Possible side effects
- Strong appetite increase (ghrelin mediated)
- Cortisol and prolactin elevation
- Water retention
- Numbness or tingling reported
This list reflects published literature and community reports. Individual responses vary. Not medical advice.
Bloodwork worth tracking
The community-standard practice is a baseline panel before starting, a recheck 8 to 12 weeks in, and another after time off. For GHRP-6, the markers most worth watching:
IGF-1fasting glucosecortisolprolactin
Typical time off: 4-8 wks
Lab panels are how a research protocol stays honest: numbers move before symptoms do. Interpretation belongs with a clinician. Not medical advice.
Lifestyle factors
None of the literature above was run on a background of poor sleep and no protein. These variables move outcomes more reliably than any compound on this site.
- Protein in the 1.6 to 2.2 g/kg range preserves lean mass through any body-composition phase.
- Resistance training 2 to 4 days per week plus 150+ minutes of weekly aerobic work reinforces whatever the protocol is doing.
- Sleep is the recovery window: 7 to 9 hours at consistent times.
- Hydration matters more than usual on compounds with GI or flushing effects: 2 to 3 liters daily.
- Track the variables that matter: weigh-ins, measurements, photos, and labs at sensible intervals.
Subcutaneous technique and practical notes
General best practice from clinical injection guidance — the same fundamentals nurses are taught, none of it specific to any compound.
References
Quick answers
How many syringe units is a 300 mcg x3 daily dose of GHRP-6?
At the standard reconstitution of 5 mg with 0.5 mL bacteriostatic water (10 mg/mL), a 300 mcg x3 daily dose draws 3 units (0.03 mL) x3 on a U-100 insulin syringe.
How do you reconstitute GHRP-6?
Add 0.5 mL of bacteriostatic water to the 5 mg vial for 10 mg/mL. Inject the water slowly down the inside wall of the vial, swirl gently without shaking, and refrigerate at 2 to 8 °C after mixing.
How long does a 5 mg vial of GHRP-6 last?
About 16 maintenance doses of 300 mcg x3 daily, roughly 0.8 weeks at three times daily subcutaneous.
Does GHRP-6 have human trial data?
Yes. The dosing on this page is anchored to published human research (GHRP-6 human growth hormone secretion studies).
How does GHRP-6 work?
The earliest of the growth-hormone-releasing hexapeptides and the compound that led to the discovery of the ghrelin receptor. It is a strong GH releaser and a strong appetite stimulant — the hunger is a pronounced, well-documented effect rather than an incidental one.
Sourcing GHRP-6
Our featured supplier does not stock this compound, and we are not going to point you at a vendor we have not looked at. Use the COA checklist on whoever you do buy from, and check the batch number on the certificate against the vial you receive.
